谷氨酰胺合成酶

• EC编号：6.3.1.2
• 通用名：谷氨酸—氨连接酶
  • 英文：glutamate—ammonia ligase
• 催化反应：ATP+L-谷氨酸+NH₃=ADP+磷酸+L-谷氨酰胺
• 系统名称：L-谷氨酸:氨连接酶(形成ADP)
  • 英文：L-glutamate:ammonia ligase (ADP-forming)
• CAS注册号：9023-70-5
• 其他名称：谷氨酰胺合成酶
• 注释：也可以很慢地作用于4-亚甲基-L-谷氨酸
• 参考：

1. Elliott, W.H. Isolation of glutamine synthetase and glutamotransferase from green peas. J. Biol. Chem. 201 (1953) 661-672.

2. Fry, B.A. Glutamine synthesis by Micrococcus pyogenes var. aureus. Biochem. J. 59 (1955) 579-589.

3. Lajtha, A., Mela, P. and Waelsch, H. Manganese-dependent glutamotransferase. J. Biol. Chem. 205 (1953) 553-564.

4. Meister, A. Glutamine synthesis, in Boyer, P.D., Lardy, H. and Myrbäck, K. (Eds.), The Enzymes, 2nd edn., vol. 6, Academic Press, New York, 1962, pp. 443-468.

5. Woolfolk, C.A., Shapiro, B. and Stadtman, E.R. Regulation of glutamine synthetase. I. Purification and properties of glutamine synthetase from Escherichia coli. Arch. Biochem. Biophys. 116 (1966) 177-192.